The Los Angeles Angels (43-43) and Toronto Blue Jays (49-38) begin a 3-game series Friday. First pitch from Rogers Centre is set for 7:07 p.m. ET (Apple TV+). Let’s analyze BetMGM Sportsbook’s MLB odds around the Angels vs. Blue Jays odds and make our expert MLB picks and predictions for the best bets.
Season series: Angels lead 2-1
The Angels beat the Atlanta Braves 5-1 on Thursday night to take the 3-game series, cashing as +132 road underdogs with the Under (9) hitting. SP José Soriano was dominant, tossing 7 scoreless innings (3 H, 2 BB, 7 K). SS Zach Neto went 3-for-5 with a double and a homer and 1B Nolan Schanuel had a 2-run blast.
The Blue Jays wrapped up a 4-game sweep of the New York Yankees with an 8-5 win Thursday night, cashing as -118 home favorites with the Over (10.5) hitting. DH George Springer led the way, going 3-for-4 with 2 HRs and 4 RBIs. OF Nathan Lukes added 2 doubles and 2 RBIs and OF Addison Barger homered as part of a 3-for-4 effort.
Angels at Blue Jays projected starters
RHP Kyle Hendricks vs. LHP Eric Lauer
Hendricks (5-6, 4.66 ERA) is making his 17th start. He has a 1.30 WHIP, 2.4 BB/9 and 6.2 K/9 in 87 innings.
- Last start: No-decision, 5 IP, 1 ER, 5 H, 0 BB, 5 K in 8-2 home victory against Washington Nationals Saturday
- 2025 road stats: 2-3, 5.44 ERA (41 1/3 IP, 25 ER), 1.33 WHIP, 7.4 K/9 in 8 starts
- Career vs. Blue Jays: 0-1, 4.32 ERA (16 2/3 IP, 8 ER), 1.26 WHIP, 7.0 K/9 in 3 starts; last faced them in 2024
Lauer (4-1, 2.60 ERA) is making his 13th appearance and seventh start. He has a 1.07 WHIP, 2.8 BB/9 and 9.0 K/9 in 45 innings.
- Last start: No-decision, 4 1/3 IP, 3 ER, 7 H, 0 BB, 4 K in 5-3 road victory against Boston Red Sox Sunday
- 2025 home stats: 1-0, 2.25 ERA (16 IP, 4 ER), 0.88 WHIP, 10.7 K/9 in 4 appearances (2 starts)
- Has never started against the Angels
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Angels at Blue Jays odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:07 a.m. ET.
- Moneyline (ML): Angels +140 (bet $100 to win $140) | Blue Jays -165 (bet $165 to win $100)
- Run line (RL)/Against the spread (ATS): Angels +1.5 (-145) | Blue Jays -1.5 (+120)
- Over/Under (O/U): 9.5 (O: -105 | U: -115)
Angels at Blue Jays picks and predictions
Prediction
Blue Jays 7, Angels 3
PASS.
I like the Blue Jays (-165) to win but not at those odds. I’ll take my wager to the run line.
BET BLUE JAYS -1.5 (+120).
The Blue Jays enter Friday’s matchup riding high after a dominant 4-game sweep of the Yankees. They have won 5 straight games and 7 of their last 8 contests. They’ve been tough to beat at Rogers Centre, where they’re 29-16, thanks to a strong .273 team batting average at home—third-best in the majors. SS Bo Bichette has been a key part of that success, hitting .328 with 9 home runs and 29 RBIs at home.
The Angels face a tough task against Lauer, especially given their struggles against southpaws, hitting just .219 as a team—the second-worst mark in MLB. While Los Angeles has shown signs of improvement, Toronto has had their number, winning 8 of the last 10 meetings. With the Blue Jays clicking on all cylinders, they should take care of business comfortably on Friday.
BET OVER 9.5 (-105).
I’m taking the Over on Friday, with strong trends backing it up. The Over has hit in 5 of the last 6 meetings between the teams. Toronto has gone Over in 8 of its last 10 games. Lauer has seen the Over cash in 2 of his last 3 starts, and Hendricks in 3 of his last 4 starts.
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