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Buffalo vs. Central Michigan prediction, odds: Wednesday MACtion picks from 10,000 simulations

Teams looking to have a say in the MAC title chase meet when the Buffalo Bulls battle the Central Michigan Chippewas in MACtion on Wednesday night. Buffalo is coming off a 28-3 win at Bowling Green on Nov. 1, while Central Michigan dropped a 24-21 decision to Western Michigan that same day. The Bulls (5-4, 4-1 MAC), who are tied with three other teams for first in the conference, are 3-1 on the road this season. The Chippewas (5-4, 3-2 MAC), who are tied for fifth in the league, are 3-0 on their home field.

Kickoff from Kelly/Shorts Stadium in Mount Pleasant, Mich., is at 7 p.m. ET on CBS Sports Network. The Chippewas are 1.5-point favorites in the latest Buffalo vs. Central Michigan odds, while the over/under for total points scored is 44.5 via SportsLine consensus. Before making any Central Michigan vs. Buffalo picks, check out the college football predictions from the SportsLine Projection Model

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The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.

Now, the model has set its sights on Buffalo vs. Central Michigan. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for Central Michigan vs. Buffalo:

Buffalo vs. Central Michigan spread

Central Michigan -1.5 at DraftKings Sportsbook

Buffalo vs. Central Michigan over/under

44.5 points

Buffalo vs. Central Michigan money line 

Central Michigan -126, Buffalo +107

Buffalo vs. Central Michigan picks

See picks at SportsLine

Buffalo vs. Central Michigan streaming 

Fubo (Try for free)  

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How to make Buffalo vs. Central Michigan picks

SportsLine’s model is going Over on the total (44.5 points). The Bulls have gone over the total in four of the last eight games, while the Chippewas have been over in three of their past four. The teams combined for 50 points in their last meeting, a 37-13 Buffalo win in 2023. 

The model has Buffalo quarterback Ta’Quan Roberson throwing for two touchdowns, while Central Michigan quarterback Joe Labas also finds the end zone more than once. The teams combine for 53 points as the Over clears in well over 60% of simulations

The model also says one side of the spread hits more than 60% of the time. You can only get that pick at SportsLine. 

So who wins Buffalo vs. Central Michigan, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the Buffalo vs. Central Michigan spread to jump on, all from the advanced model that finished up over $2,000 on its FBS college football picks since its inception, and find out.

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